2-Aminotetralin

2-Aminotetralin

2-Aminotetralin
Systematic (IUPAC) name
1,2,3,4-tetrahydronaphthalen-2-amine
Clinical data
Legal status
  • Uncontrolled
Routes of
administration
Oral
Identifiers
CAS Registry Number  N
ATC code None
PubChem CID:
ChemSpider  YesY
ChEMBL  YesY
Chemical data
Formula C10H13N
Molecular mass 147.217 g/mol
 N   

2-Aminotetralin (2-AT), also known as 1,2,3,4-tetrahydronaphthalen-2-amine (THN), is a stimulant drug with a chemical structure consisting of a tetralin group combined with an amine.[1][2]

2-AT is a rigid analogue of phenylisobutylamine and fully substitutes for d-amphetamine in rat discrimination tests, although at one eighth the potency.[1] It has been shown to inhibit the reuptake of serotonin and norepinephrine, and likely induces their release as well.[3][4] It is also likely to act on dopamine on account of its full substitution of d-amphetamine in rodent studies.[1]

Chemical derivatives

A number of derivatives of 2-aminotetralin exist, including:

See also

References

  1. ^ a b c
  2. ^
  3. ^
  4. ^