BEST2

Bestrophin 2
Identifiers
BEST2 Gene
RNA expression pattern

Bestrophin-2 is a protein that in humans is encoded by the BEST2 gene.[1][2][3]

Function

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the non-pigmented ciliary epithelium and colon.[4][3]

References

Further reading