Chloride potassium symporter

The chloride potassium symporter is a membrane transport protein that is present in the S3-segment of the renal proximal tubule[1] and in the neuron.[2] It functions in renal chloride reabsorption to transport chloride across the basolateral membrane.[1]

They can lower intracellular chloride concentrations below the electrochemical equilibrium potential.[2]

They are of solute carrier family 12.

Types

Types of chloride potassium symporter are:

Each is encoded by a separate gene.

The preceding symporters are actually other types of ion pumps. Member 3, for instance, is the sodium-chloride symporter.

References