Dopamine receptor antagonist

A dopamine antagonist is a drug which blocks dopamine receptors by receptor antagonism. There are five known types of dopamine receptors in the human body; they are found in the brain, peripheral nervous system, blood vessels, gastrointestinal tract[1] and the kidney.

Uses and examples

Dopamine receptor antagonists are used for some diseases such as schizophrenia, bipolar disorder, nausea and vomiting. It can also control the symptoms of hypersexuality and increased orgasmic activity.

Antidopaminergics such as haloperidol can be an antidote for poisoning with cocaine, amphetamines and dopamine agonists such as Bromocriptine and/or Ropinirole.

Side effects

They may include one or more of the following and last indefinitely even after cessation of the dopamine antagonist, especially after long-term or high-dosage use:

Examples

Examples of Dopamine antagonists include:[2]

See also

References

External links

  • Medical Subject Headings (MeSH)
ar:مستقبلات الدوبامين