EDMA

EDMA

EDMA
Systematic (IUPAC) name
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-methylpropan-2-amine
Clinical data
Legal status
Routes Oral
Identifiers
ATC code None
PubChem
ChemSpider  YesY
Chemical data
Formula C12H17NO2 
Mol. mass 207.269
 YesY   

3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the amphetamine class.[1][2] It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring.[1][2] EDMA was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, the dosage is listed as 150–250 mg, and the duration listed as 3–5 hours.[1] According to Shulgin, EDMA produces a bare threshold consisting of paresthesia, nystagmus, and hypnogogic imagery, with few to no other effects.[1] Scientific research has demonstrated that EDMA acts as a non-neurotoxic serotonin releasing agent with moderately diminished potency relative to MDMA, and with negligible effects on dopamine release.[2] Based on Shulgin's reports of essential inactivity at 150–250 mg, it may be more active at higher doses.

See also

References

  1. ^ a b c d e Ann Shulgin; Alexander Shulgin (1991). Pihkal: A Chemical Love Story. Transform Press.  
  2. ^ a b c McKenna DJ, Guan XM, Shulgin AT (March 1991). "3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine". Pharmacology, Biochemistry, and Behavior 38 (3): 505–12.  

External links

  • PiHKALEDMA entry in
  • MDMC (EDMA) entry in PiHKAL • info