FZD9

FZD9

Frizzled class receptor 9
Identifiers
Symbols  ; CD349; FZD3
External IDs IUPHAR: GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Frizzled-9 is a protein that in humans is encoded by the FZD9 gene.[1][2][3] FZD9 has also been designated as CD349 (cluster of differentiation 349). Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.[3]

See also

References

  1. ^ Wang YK, Samos CH, Peoples R, Perez-Jurado LA, Nusse R, Francke U (May 1997). "A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23". Hum Mol Genet 6 (3): 465–72.  
  2. ^ Wang YK, Sporle R, Paperna T, Schughart K, Francke U (May 1999). "Characterization and expression pattern of the frizzled gene Fzd9, the mouse homolog of FZD9 which is deleted in Williams-Beuren syndrome". Genomics 57 (2): 235–48.  
  3. ^ a b "Entrez Gene: FZD9 frizzled homolog 9 (Drosophila)". 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.