GRID1

Glutamate receptor, ionotropic, delta 1
Identifiers
GRID1 Gene
RNA expression pattern

Glutamate receptor delta-1 subunit also known as GluD1 or GluRδ1 is a protein[1][2] that in humans is encoded by the GRID1 gene.[3][4]

Function

This gene encodes a subunit of glutamate receptor ligand-gated ion channel. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[3]

Clinical significance

Several genetic epidemiology studies have shown a strong association between several variants of the GRID1 gene and increased risk of developing schizophrenia.[5][6]

See also

References

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.