KML-010

KML-010

KML-010
Systematic (IUPAC) name
8-[4-(4-fluorophenyl)-4-oxobutyl]-1-methyl-1,3,8-triazaspiro[4.5]decan-4-one
Clinical data
Legal status
?
Identifiers
ATC code ?
PubChem
ChemSpider  YesY
Chemical data
Formula C18H24FN3O2 
Mol. mass 333.400 g/mol
 YesY   

KML-010 is a drug derived from spiperone. It functions as a highly selective 5-HT2A receptor antagonist, with negligible affinity for the 5-HT1A or 5-HT2C receptors, and over 400-fold lower affinity for the D2 receptor in comparison to spiperone.[1]

See also

References

  1. ^ Glennon RA, Metwally K, Dukat M, Ismaiel AM, De los Angeles J, Herndon J, Teitler M, Khorana N (June 2002). "Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists". Current Topics in Medicinal Chemistry 2 (6): 539–58.