Mebhydrolin

Mebhydrolin

Mebhydrolin
Systematic (IUPAC) name
5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
Clinical data
AHFS/Drugs.com
Pregnancy
category
  • Not established[1]
Routes of
administration
oral[1]
Identifiers
CAS Registry Number  N 6153-33-9[2]
ATC code R06
PubChem CID:
ChemSpider  Y
UNII  Y
KEGG  Y
Synonyms 9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Chemical data
Formula C19H20N2 [4]
Molecular mass 276.376 g/mol
 N   

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries. It is also called Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.[5]

References

  1. ^ a b "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Retrieved 2007-03-02. 
  2. ^ "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02. 
  3. ^ "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02. 
  4. ^ "Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02. 
  5. ^ Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9.