Minaprine

Minaprine

Minaprine
Systematic (IUPAC) name
4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
Clinical data
AHFS/Drugs.com
Legal status
  • (Prescription only)
Routes of
administration
Oral
Pharmacokinetic data
Biological half-life 2-2.5 hours
Identifiers
CAS Registry Number  YesY
ATC code N06
PubChem CID:
ChemSpider  N
UNII  N
KEGG  YesY
ChEMBL  N
Chemical data
Formula C17H22N4O
Molecular mass 298.383 g/mol
 N   

Minaprine (Brantur, Cantor) is an antidepressant that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.[1]

A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats.[2] In a study it has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.[3]

See also

References

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