Solute carrier family 22 (organic cation transporter), member 1
SLC22A1 Gene
RNA expression pattern

Solute carrier family 22 member 1 is a protein that in humans is encoded by the SLC22A1 gene.[1][2]

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.[2]

See also


Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.