SLC6A12

BCCT family transporter
PDB 3p03
Identifiers
Symbol BCCT
Pfam InterPro TCDB OPM superfamily OPM protein 3fhx

Betaine / Carnitine / Choline Transporters (BCCT) are a family of prokaryotic transport proteins that are specific for compounds containing a quaternary nitrogen atom. The BCCT proteins contain 12 transmembrane regions and are energized by sodium symport. They contain a conserved region with four tryptophans in their central region.[1] All structures solved to date are trimeric.

The mammalian betaine transporter (SLC6A12) is regulated by NFAT5 during response to osmotic stress.[2]

References

This article incorporates text from the IPR000060