17β-Hydroxysteroid dehydrogenase

17β-Hydroxysteroid dehydrogenase

17β-Hydroxysteroid dehydrogenase
Identifiers
EC number CAS number IntEnz BRENDA ExPASy KEGG MetaCyc metabolic pathway
PRIAM PDB structures PDBsum
Gene Ontology EGO


17β-Hydroxysteroid dehydrogenases (

Note that the major reactions catalysed by 17β-HSD (e.g., the conversion of androstenedione to testosterone) are in fact hydrogenation (reduction) rather than dehydrogenation (oxidation) reactions.

Genes

Genes coding for 17β-HSD include:

Clinical significance

Isozyme 3 is responsible for 17-beta-hydroxysteroid dehydrogenase deficiency.

References

  • Medical Subject Headings (MeSH)

External links

  • Medical Subject Headings (MeSH)