3,4-Dihydroxystyrene

3,4-Dihydroxystyrene

3,4-Dihydroxystyrene
Systematic (IUPAC) name
4-vinylbenzene-1,2-diol
Clinical data
Legal status
  • Uncontrolled
Identifiers
CAS number  N
ATC code None
PubChem
ChemSpider  YesY
KEGG  YesY
Chemical data
Formula C8H8O2 
Mol. mass 136.15 g/mol
 N   

3,4-Dihydroxystyrene (DHS) is a centrally-acting inhibitor of the enzyme phenylalanine hydroxylase (PH).[1] It is likely that DHS and other PH inhibitors will never have clinical applications on account of their capacity for inducing hyperphenylalaninemia and phenylketonuria.

See also

References

  1. ^ Koizumi S, Matsushima Y, Nagatsu T, Iinuma H, Takeuchi T, Umezawa H (September 1984). "3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases". Biochimica Et Biophysica Acta 789 (2): 111–8.