4'-Methyl-α-pyrrolidinohexiophenone

4'-Methyl-α-pyrrolidinohexiophenone

4'-Methyl-α-pyrrolidinohexiophenone
Systematic (IUPAC) name
(RS)-1-(4-methylphenyl)-2-(1-pyrrolidinyl)-1-hexanone
Clinical data
Legal status
Identifiers
PubChem CID:
ChemSpider
Chemical data
Formula C17H25NO
Molecular mass 259.385 g/mol

4'-Methyl-α-pyrrolidinohexiophenone or MPHP is a stimulant compound which has been reported as a novel designer drug.[1][2][3] It is closely related to pyrovalerone, being simply its chain-lengthened homologue. In the pyrrolidinophenone series, stimulant activity is maintained so long as the positions of the aryl, ketone and pyrrolidinyl groups are held constant, while the alkyl backbone can be varied anywhere between three to as many as seven carbons,[4] with highest potency usually seen with the pentyl or isohexyl backbone, and a variety of substituents are tolerated on the aromatic ring.[5]

In 2010 a group of researchers from the Institute of Forensic Medicine, University Hospital Jena, Germany concluded that MPHP can lead to serious poisoning with toxic liver damage and rhabdomyolysis.[6]

Legality

Sweden's public health agency suggested to classify MPHP as narcotic on June 1, 2015.[7]

See also

References

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  4. ^ GB patent 1149366, "α-substituted-ketones and processes for their preparation." 
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