Systematic (IUPAC) name
Clinical data
Legal status
Chemical data
Formula C13H19NO
Molecular mass 205.14 g/mol

4-Methylpentedrone (also known as 4-MPD and 4-Methyl-α-methylamino-valerophenone), is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1] It is a higher homologue of 4-Methylmethcathinone (Mephedrone) and 4-Methylbuphedrone (4-MeMABP), and the p-Methyl analogue of Pentedrone.

4-MPD acts as a reuptake inhibitor for dopamine and norepinephrine without causing release.[2]

Another compound, 4-Methyl-N-Ethyl-Pentedrone (4-MEAP, 4-MEAPP) has been found to be incorrectly sold as 4-Methylpentedrone.[3][4]

See also


  1. ^ "4-Methylpentedrone". Cayman Chemical. Retrieved 28 June 2015. 
  2. ^ L.D. Simmler, A. Ricklia, M.C. Hoener, M.E. Liechti (April 2014). "Monoamine transporter and receptor interaction profiles of a new series of designer cathinones". Neuropharmacology 79: 152–160.  
  3. ^ Danielle Hamby M.Sc, Annessa Burnett B.S, Michael Jablonsky Ph.D, Brendan Twamley Ph.D, Pierce V. Kavanagh Ph.D, Elizabeth A. Gardner Ph.D (May 2015). "Identification of 2-(ethylamino)-1-(4-methylphenyl)-1-pentanone (4-MEAP), a New “Legal High” Sold by an Internet Vendor as 4-Methyl Pentedrone". Journal of Forensic Sciences 60 (3): 721–726,.  
  4. ^ Nahoko Uchiya, Satoru Matsuda, Maiko Kawamura, Yoshihiko Shimokawa, Ruri Kikura-Hanajiri, Kosuke Aritake, Yoshihiro Urade, Yukihiro Goda (October 2014). "Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products". Forensic Science International 243: 1–13.