5-MeO-DiBF

5-MeO-DiBF

5-MeO-DiBF
Systematic (IUPAC) name
2-(5-Methoxy-1-benzofuran-3-yl)-N,N-diisopropyllethanamine
Chemical data
Formula C17H25NO2
Molecular mass 275.381 g/mol

5-MeO-DiBF is a psychedelic[1] that has been sold online as a designer drug. It acts as an agonist for the 5-HT1A and 5-HT2 family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DiPT, but with the indole nitrogen replaced by oxygen, making 5-MeO-DiBF a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DiPT and with relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.[2][3]

See also

References

  1. ^ John F. Casale, Patrick A. Hays. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal 9 (1): 39–45. 
  2. ^ Zbigniew Tomaszewski , Michael P. Johnson , Xuemei Huang , David E. Nichols (May 1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry 35 (11): 2061–2064.  
  3. ^ D.J. Mckenna, D.B. Repke, L. Lo, S.J. Peroutka (March 1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology 29 (3): 193–198.