|Molar mass||115.13 g/mol|
|Appearance||white crystalline powder|
|Melting point||265 °C (509 °F; 538 K)|
|Boiling point||231 °C (448 °F; 504 K)|
|Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)|
Allylglycine is a glycine derivative. It is an inhibitor of the enzyme glutamate decarboxylase. Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter. Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity.
- Abshire VM, Hankins KD, Roehr KE, DiMicco JA (November 1988). "Injection of L-allylglycine into the posterior hypothalamus in rats causes decreases in local GABA which correlate with increases in heart rate". Neuropharmacology 27 (11): 1171–7.
- Sajdyk T, Johnson P, Fitz S, Shekhar A (August 2008). "Chronic inhibition of GABA synthesis in the bed nucleus of the stria terminalis elicits anxiety-like behavior". J. Psychopharmacol. (Oxford) 22 (6): 633–41.
- Thomas J, Yang YC (June 1991). "Allylglycine induced seizures in male and female rats". Physiol Behav. 49 (6): 1181–3.