BHFF
Systematic (IUPAC) name
5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone
Clinical data
Legal status
?
Identifiers
CAS number  YesY
ATC code ?
PubChem
ChemSpider  YesY
Chemical data
Formula C17H21F3O3 
Mol. mass 330.341 g/mol
 YesY   

BHFF is a compound used in scientific research which acts as a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and good oral bioavailability.[1]

References

  1. ^ Malherbe, P; Masciadri, R; Norcross, RD; Knoflach, F; Kratzeisen, C; Zenner, MT; Kolb, Y; Marcuz, A; Huwyler, J (2008). "Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors". British Journal of Pharmacology 154 (4): 797–811.