Beta-Bungarotoxin

Beta-Bungarotoxin

β2-Bungarotoxin
Beta2-bungarotoxin
Identifiers
CAS number  N
β1:65862-89-7
β2:82446-04-6
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N   YesY/N?)

β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus)venoms.

The target of this neurotoxin is at the presynaptic terminal, where it blocks release of acetylcholine. There are two isoforms, β1-bungarotoxin and β2-bungarotoxin. It has phospholipase A2 activity.

It consists of two chains.[1]

References

  1. ^ Cheng YC, Wang JJ, Chang LS (February 2008). "B chain is a functional subunit of beta-bungarotoxin for inducing apoptotic death of human neuroblastoma SK-N-SH cells". Toxicon 51 (2): 304–15.