Butaclamol

Butaclamol

Butaclamol
Systematic (IUPAC) name
3-(1,1-dimethylethyl)-2,3,4,4a,8,9, 13b,14-octahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3-ol
Clinical data
Legal status
?
Identifiers
CAS number
ATC code None
PubChem
IUPHAR ligand
ChemSpider
UNII  YesY
ChEBI  YesY
ChEMBL  YesY
Chemical data
Formula C25H31NO 
Mol. mass 361.52 g/mol

Butaclamol (AY-23,028) is an [1] Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist. [2]

Chemistry

pKa = 7.15 (uncorrected for ionic strength)[3]


See also

References

  1. ^ Dictionary of organic compounds - Google Books. 
  2. ^ http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&N4=D033%7CSIGMA&N25=0&QS=ON&F=SPEC
  3. ^ F. A. Chrzanowski, B. A. McGrogan, B. E. Maryanoff (1985). "The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors." J. Med. Chem. 28 399-400.