CP-1414S

CP-1414S

CP-1414S
Systematic (IUPAC) name
1-phenyl-4-amino-8-nitro-3H-1,5-benzodiazepin-2-one
Clinical data
Legal status
?
Identifiers
CAS number  YesY
ATC code None
PubChem
ChemSpider  YesY
Chemical data
Formula C15H12N4O3 
Mol. mass 296.280
 YesY   

CP-1414S is an experimental drug first made by a team in Germany.[1] It is a benzodiazepine derivative. CP-1414S is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring, and so is most closely related to other 1,5-benzodiazepines such as clobazam.

CP-1414S has primarily anxiolytic and anticonvulsant effects.[2] Its potency is roughly equal to that of clobazam, but with more pronounced sedation.[3]

See also

References

  1. ^ US 3766169
  2. ^ Carli M, Ballabio M, Caccia S, Garattini S, Samanin R (1981). "Studies on some pharmacological activities of 7-nitro-2-amino-5-phenyl-3H-1,5-benzodiazepine (CP 1414 S) in the rat. A comparison with diazepam". Arzneimittel-Forschung 31 (10): 1721–3.  
  3. ^ Mennini T, Garattini S (November 1982). "Benzodiazepine receptors': correlation with pharmacological responses in living animals". Life Sciences 31 (19): 2025–35.