CATSPER1

Cation channel, sperm associated 1
Identifiers
CATSPER1 Gene
Orthologs
SpeciesHumanMouse

CatSper1, is a protein which in humans is encoded by the CATSPER1 gene.[1][2][3] CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.[4]

Function

Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region.[5]

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.