Cefminox
Systematic (IUPAC) name
(6R,7S)-7-(((((2S)-2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com
Legal status
  • Prescription only
Routes IM, IV
Identifiers
CAS number  YesY
ATC code J01
PubChem
ChemSpider  N
UNII  YesY
KEGG  YesY
ChEMBL  N
Chemical data
Formula C16H21N7O7S3 
Mol. mass 519.57 g/mol
 N   

Cefminox (INN) is a second-generation cephalosporin antibiotic.[1][2]

Spectrum

Cefminox is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria. The following represents MIC data for a few medically significant microorganisms.

  • Clostridium difficile: 2 - 4 µg/ml
  • Escherichia coli: 0.125 - 16 µg/ml
  • Pseudomonas aeruginosa: 256 µg/ml

[3]

References

  1. ^ Torres, A. J.; Valladares, L. D.; Jover, J. M.; Sánchez-Pernaute, A.; Frías, J.; Carcas, A. J.; Coronel, P.; Ródenas, E.; Pérez-Balcabao, I.; Fernández-Roblas, R.; Moreno, M.; Balibrea, J. L. (2000). "Cefminox versus metronidazole plus gentamicin intra-abdominal infections: A prospective randomized controlled clinical trial". Infection 28 (5): 318–322.  
  2. ^ Patentdocs: Reaction Medium For Methicillin-Resistant Staphylococcus Aureus (Mrsa) Bacteria
  3. ^ http://www.toku-e.com/Assets/MIC/Cefminox%20sodium.pdf