Combination of
Clindamycin phosphate Antibiotic
Tretinoin Topical retinoid
Clinical data
Licence data US FDA:
Pregnancy cat.
Legal status
  • Prescription only
Routes Topical
ATC code D10

The drug combination clindamycin/tretinoin (trade name Ziana and Veltin) is a topical acne treatment. It combines clindamycin phosphate (1.2%), an antibiotic, and tretinoin (0.025%), a retinoid.[1] There is a generic form. It comes in 2, 30, and 60 gram tubes and should be stored at 77 degrees F, with the tube tightly shut away from light.[2] Side effects may include peeling, redness, dryness, itching and photosensitivity. Also, topical clindamycin may rarely cause diarrhea or colitis. Using this preparation in presence of sunlight can cause irritation. So it is better to apply in evening or at night.


  1. ^ "Ziana Gel". Retrieved 2008-11-16. 
  2. ^ "ZIANA Prescribing Information". Retrieved 2008-11-15. 

External links

  • Official Website