Desonide

Desonide

Desonide
Systematic (IUPAC) name
(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Clinical data
Trade names Desowen
AHFS/Drugs.com
MedlinePlus
Pregnancy
category
  • US: C (Risk not ruled out)
Legal status
Routes of
administration
topical
Identifiers
CAS Registry Number  Y
ATC code D07 S01
PubChem CID:
IUPHAR/BPS
DrugBank  Y
ChemSpider  Y
UNII  Y
KEGG  Y
ChEBI  Y
ChEMBL  N
Synonyms (11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Chemical data
Formula C24H32O6
Molecular mass 416.507 g/mol
 N   

Desonide is the generic name of a low-potency topical corticosteroid that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile[1] and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. It is a group VI corticosteroid under US classification, the second least potent group.

References

  1. ^ Wong, Vicky Kwan; Brian Fuchs;