Molecular formula C17H18ClN5O2S2
Molar mass 423.94 g mol-1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)

E-6801 is a partial agonist of the 5-HT6 receptor.[1] It enhanced recognition memory and reversed the memory deficits of scopolamine in an object recognition task in a rat model.[2] The mechanism of memory enhancement is due to a combined modulation of cholinergic and glutamatergic neurotransmission.

See also


  1. ^ Romero, G. (August 2006). "Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways".  
  2. ^ Kendall, I. (February 2011). "E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat.". Psychopharmacology 213 (2-3): 413–30.