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Endogenous substances are those that originate from within an organism, tissue, or cell.
Endogenous viral elements (EVEs) are DNA sequences derived from viruses that are ancestrally inserted into the genomes of germ cells. These sequences, which may be fragments of viruses, or entire viral genomes (proviruses), can persist in the germline, being passed on from one generation to the next as host alleles.
In some biological systems, endogeneity refers to the recipient of DNA (usually in prokaryotes). However, because of homeostasis, discerning between internal and external influences is often difficult.
Endogenous transcription factors refers to those that are manufactured by the cell, as opposed to cloned transcription factors.
The word endogenous // derives from the Greek: ενδογενής, meaning "proceeding from within" ("ενδο"=inside "-γενής"=coming from), the complement of exogenous (Greek: εξωγενής exo, "έξω"= outside) "proceeding from outside".