Escaline

Escaline

Escaline
Names
IUPAC name
2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine
Other names
3,5-Dimethoxy-4-ethoxy-phenethylamine
2-(4-Ethoxy-3,5-dimethoxyphenyl)ethanamine
Identifiers
 YesY
ChEMBL  YesY
ChemSpider  YesY
Jmol-3D images Image
Image
PubChem
Properties
C12H19NO3
Molar mass 225.28 g/mol
Melting point 165 to 166 °C (329 to 331 °F; 438 to 439 K) (hydrochloride)
 YesY  (: YesY/N?)

Escaline or 3,5-methoxy-4-ethoxyphenethylamine is a psychedelic drug and entheogen of the phenethylamine class of compounds. Escaline was first synthesized and reported in the scientific literature by Benington, et al., in 1954, but was later re-examined in the laboratory of David E. Nichols, who prepared a series of mescaline analogues that included escaline, proscaline, and isoproscaline. The effects of this and related mescaline analogues in humans were first described by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as 40 to 60 mg, consumed orally. The duration of action was stated to be 8