Fenmetozole (DH-524) is a drug which was patented as an antidepressant,[1][2] but was later studied as an antagonist of the effects of ethanol, though results were poor and it even increased its effects in some cases.[3][4][5][6][7] It acts as an α2-adrenergic receptor antagonist similarly to other imidazoles like idazoxan.[8] It was never marketed.[2]