GABRA6

GABRA6

Gamma-aminobutyric acid (GABA) A receptor, alpha 6
Identifiers
GABRA6 Gene
RNA expression pattern

Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene.[1][2]

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.[2]

One study has found a genetic variant in the gene to be associated with the personality trait neuroticism.[3]

See also

References

Further reading

External links

  • Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.