GBR-13098

GBR-13098

GBR-13098
Names
IUPAC name
1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-[3-(4-fluorophenyl)propyl]piperazine
Identifiers
ChemSpider
Jmol-3D images Image
PubChem
Properties
C28H31F3N2O
Molar mass 468.56 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor.[1]

Blocking the endogenous striatal dopamine (DA) transporter with GBR-13098 in mice has been shown to prevented damage to the DA nerve terminals caused by malonate. It was suggested that DA transporter inhibitors like GBR-13098 could be used to prevent or treat neruodegenerative disorders caused by the effect of mitochondrial dysfunction on DA homeostasis.[2]

See also

References

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