G protein-coupled receptor 182
GPR182 Gene
RNA expression pattern

GPR182 (or G protein-coupled receptor 182) is a human gene (and associated protein) which is an orphan G-protein coupled receptor.[1]

When this gene was first cloned, it was proposed to encode an adrenomedullin receptor.[2] However when the corresponding protein was expressed, it was found not to respond to adrenomedullin (ADM).[3]

It was subsequently shown that a different GPCR, CALCRL when complexed with RAMP2 can function as an ADM receptor.[4]


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