JNJ-5207852

JNJ-5207852

JNJ-5207852
Identifiers
Abbreviations JNJ-5207852
PubChem 2766326 YesY
ChemSpider 2046959 YesY
MeSH JNJ-5207852
ChEBI CHEBI:312531 YesY
Jmol-3D images Image 2
Properties
Molecular formula C20H32N2O
Molar mass 316.480 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

JNJ-5207852 is a histamine antagonist selective for the H3 subtype. It has stimulant and nootropic effects in animal studies,[1] and has been suggested as a possible treatment for memory defects associated with epilepsy.[2] JNJ-5207852 itself did not progress to clinical development due to poor pharmacokinetic characteristics, but the related compound JNJ-17216498 is currently in Phase II clinical trials for the treatment of narcolepsy.[3]

References