JWH-149

JWH-149

JWH-149
Systematic (IUPAC) name
(4-methyl-1-naphthalenyl)(2-methyl-1-pentyl-1H-indol-3-yl)methanone
Identifiers
CAS Registry Number  YesY
PubChem CID:
ChemSpider
Chemical data
Formula C26H27NO
Molecular mass 369.50 g/mol

JWH-149 is a synthetic cannabimimetic that was discovered by John W. Huffman. It is the N-pentyl analog of JWH-148. It is a potent but only moderately selective ligand for the CB2 receptor, with a binding affinity of Ki = 0.73 ± 0.03 nM at this subtype, and more than 6 times selectivity over the CB1 subtype.[1]

See also

References

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