JWH-167

JWH-167

JWH-167
Names
IUPAC name
2-phenyl-1-(1-pentylindol-3-yl)ethanone
Other names
1-(1-pentyl-1H-indol-3-yl)-2-phenylethanone
Identifiers
 N
ChEMBL  YesY
ChemSpider  YesY
Jmol-3D images Image
PubChem
Properties
C21H23NO
Molar mass 305.42 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N  (: YesY/N?)

JWH-167 (1-pentyl-3-(phenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about 1.75x selectivity for CB1 with a Ki of 90nM ± 17 and 159nM ± 14 at CB2. Similar to the related 2'-methoxy compound JWH-250, and the 2'-chloro compound JWH-203, JWH-167 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.[1][2]

References

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