L-AP4

L-AP4

L-AP4
Systematic (IUPAC) name
(2S)-2-amino-4-phosphonobutanoic acid
Identifiers
CAS Registry Number  YesY
PubChem CID:
IUPHAR/BPS
ChemSpider  N
Chemical data
Formula C4H10NO5P
Molecular mass 183.099 g/mol
 N   

L-2-amino-4-phosphonobutyric acid (or L-AP4) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors,[1] but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions.[2][3][4][5]

References

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