Levopropylhexedrine

Levopropylhexedrine

Levopropylhexedrine
Systematic (IUPAC) name
(S)-1-cyclohexyl-N-methylpropan-2-amine
Clinical data
Legal status
  • Prescription only
Routes Oral
Identifiers
CAS number
ATC code None
PubChem
ChemSpider
UNII  YesY
Chemical data
Formula C10H21N 
Mol. mass 155.28 g/mol

Levopropylhexedrine (Eventin) is a psychostimulant used as an anorectic in Germany[1][2] and patented by Smith Kline & French in 1947.[3] It has also been used in the anticonvulsant preparation barbexaclone in combination with phenobarbital to offset sedation.[4][5][6] Levopropylhexedrine is the S-enantiomer of propylhexedrine.

See also

References

  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers.  
  2. ^ Hofer R, Locker A (1958). "Über therapeutische Erfahrungen mit dem Appetitzügler Eventin" [Therapeutic experiences with the appetite depressant eventin]. Wiener Medizinische Wochenschrift (in German) 108 (14): 304–6.  
  3. ^ US 2454746 Cyclohexylalkylamines
  4. ^ Oliveira C, Fernandes I, De Lima JM, Musse R (1977). "Ensaio clínico com barbexaclone nas epilepsias" [Clinical trial with barbexaclone in epilepsies]. Arquivos De Neuro-Psiquiatria (in Portuguese) 35 (1): 68–72.  
  5. ^ Iven H, Feldbusch E (1983). "Pharmacokinetics of phenobarbital and propylhexedrine after administration of barbexaclone in the mouse". Naunyn-Schmiedeberg's Archives of Pharmacology 324 (2): 153–9.  
  6. ^ Seyffart, G. (1991). Drug dosage in renal insufficiency. Boston: Kluwer Academic Publishers.