Lopirazepam

Lopirazepam

Lopirazepam
Systematic (IUPAC) name
(RS)-7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-pyrido[3,2-e][1,4]diazepin-2-one
Clinical data
Pregnancy cat.
  • D
Legal status
Routes Oral
Identifiers
CAS number
ATC code None
PubChem
ChemSpider
UNII  YesY
Chemical data
Formula C14H9Cl2N3O2 
Mol. mass 322.146 g/mol

Lopirazepam (INN)[1] is a short-acting benzodiazepine analog of the pyridodiazepine type (specifically, the pyridodiazepine analog of lorazepam) with anxiolytic and hypnotic properties.[2][3] It has never been marketed.[4]

See also

References

  1. ^ US Patent 4008223
  2. ^ Saletu M, Saletu B, Grünberger J, Mader R, Karobath M (1983). "Clinical symptomatology and computer analyzed EEG before, during and after anxiolytic therapy of alcohol withdrawal patients". Neuropsychobiology 9 (2–3): 119–34.  
  3. ^ Fabian A, Röhmel R, Kubicki S (September 1984). "[Changes in the length of sleep cycles during administration of flurazepam and lopirazepam]". EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb (in German) 15 (3): 151–8.  
  4. ^ David J. Triggle; C. R. Ganellin; F. MacDonald (1996). Dictionary of Pharmacological Agents 2. Boca Raton: Chapman & Hall/CRC. p. 1232.   Retrieved on December 31, 2008 through Google Book Search.