Loteprednol

Loteprednol

Loteprednol etabonate
Systematic (IUPAC) name
Chloromethyl 17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
Clinical data
AHFS/Drugs.com
MedlinePlus
Pregnancy
category
  • US: C (Risk not ruled out)
Legal status
Identifiers
CAS Registry Number  YesY
ATC code S01
PubChem CID:
IUPHAR/BPS
DrugBank  N
ChemSpider  N
UNII  N
KEGG  YesY
ChEMBL  N
Chemical data
Formula C24H31ClO7
Molecular mass 466.951 g/mol
 N   

Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used in ophthalmology. Marketed by Bausch and Lomb as Lotemax in the U.S., ocular applications for this drug include the treatment of inflammation of the eye due to allergies (according to the prescription information sheet), as well as chronic forms of keratitis (e.g.: adenoviral and Thygeson’s keratitis), vernal keratoconjunctivitis, pingueculitis, and episcleritis. The drug has little or no effect on intraocular pressure.

See also

References



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