PHA-57378

PHA-57378

PHA-57378
Systematic (IUPAC) name
2,7,8,9,10,11-hexahydro-1H-azepino[4,5-b][1,4]oxazino[2,3,4-hi]indole
Identifiers
CAS Registry Number  YesY
PubChem CID:
ChemSpider
Chemical data
Formula C14H16N2O
Molecular mass 228.29 g/mol

PHA-57378 is a drug which acts as an agonist at serotonin 5-HT2 receptors,[1] having a binding affinity of 4.1 nM at the 5-HT2A subtype and 4.3 nM at 5-HT2C. It has anxiolytic effects in animal studies.[2]

See also

References

  1. ^ Jackson Hester et al. TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS. WIPO Patent Application WO 2000/064899, Priority date April 23, 1999
  2. ^