PRX-03140

PRX-03140

PRX-03140
Systematic (IUPAC) name
4-hydroxy-7-isopropyl-6-oxo-N-[3-(1-piperidinyl)propyl]-6,7-dihydrothieno[2,3-b]pyridine-5-carboxamide
Clinical data
Legal status
?
Identifiers
CAS number
ATC code None
PubChem
ChemSpider
Chemical data
Formula C19H27N3O3S 
Mol. mass 377.501 g/mol

PRX-03140 is a partial agonist (18% relative to 5-HT[1]) of the 5-HT4 receptor that is being developed by EPIX Pharmaceuticals for Alzheimer's disease.[2]

References

  1. ^ Shen F, Smith JA, Chang R, et al. (2011). "5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment". Neuropharmacology 61 (1-2): 69–79.  
  2. ^ Shen, F (August 2011). "5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment.". Neuropharmacology 61 (1-2): 69–79.