|Systematic (IUPAC) name|
|Biological half-life||2.6 to 16 hours, mean 5.7 hours|
|CAS Registry Number|
Pentostatin (or deoxycoformycin, trade name Nipent, manufactured by SuperGen) is an anticancer chemotherapeutic drug.
Cancer cells generally divide more often than healthy cells; DNA is highly involved in cell division (mitosis) and drugs which target DNA-related processes are therefore more toxic to cancer cells than healthy cells.
Additionally, pentostatin has been used to treat steroid-refractory acute and chronic graft-versus-host disease.
Pentostatin is also used in chronic lymphocytic leukemia (CLL) patients who have relapsed.