|Jmol-3D images||Image 1|
|Molar mass||295.85 g mol−1|
| (what is: / ?) |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Pitolisant (INN) or tiprolisant (USAN) is a histamine receptor inverse agonist/antagonist selective for the H3 subtype. It has stimulant and nootropic effects in animal studies, and may have several medical applications, having been researched for the treatment of narcolepsy, for which it has been granted orphan drug status in the EU and US. It is currently in clinical trials for schizophrenia and Parkinson's disease.
Pitolisant was developed by Jean-Charles Schwartz and colleagues after the former discovered H3 receptors. Pitolisant was the first clinically used H3 receptor inverse agonist.