Platelet-activating factor receptor

Platelet-activating factor receptor

Platelet-activating factor receptor
Available structures
PDB Ortholog search: RCSB
RNA expression pattern

The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor.[1][2]

The PAF receptor shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.[supplied by OMIM][3]


Further reading

External links

  • Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.