Prolintane

Prolintane

Prolintane
Systematic (IUPAC) name
1-(1-benzylbutyl)pyrrolidine
Clinical data
Legal status
?
Identifiers
CAS number  N
ATC code N06
PubChem
ChemSpider  YesY
UNII  YesY
Chemical data
Formula C15H23N 
Mol. mass 217.35 g/mol
 N   

Prolintane (Catovit) is a stimulant[1] of norepinephrine-dopamine reuptake inhibitors developed in the 1950s[2] which is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine and with a similar mechanism of action. It is a mild stimulant with a very good safety profile.[3] The good safety profile of this drug makes it suitable for use in elderly people to increase motivation and counteract the effects of senile dementia and age-related cognitive decline.[4] However the drug has now been banned in European countries. Prolintane is a nootropic with a better safety profile than propylhexedrine, cyclopentamine and caffeine. Many cases of prolintane abuse have been reported.[5]

See also

References

  1. ^ Hollister, L. E.; Gillespie, H. K. (1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of Clinical Pharmacology 10 (2): 103–109.  
  2. ^ GB Patent 807835
  3. ^ Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). "Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline". British Journal of Clinical Pharmacology 10 (5): 465–472.  
  4. ^ Kuitunen, T.; Kärkkäinen, S.; Ylitalo, P. (1984). "Comparison of the acute physical and mental effects of ephedrine, fenfluramine, phentermine and prolintane". Methods and Findings in Experimental and Clinical Pharmacology 6 (5): 265–270.  
  5. ^ http://www.ncbi.nlm.nih.gov/pubmed/17725890