Promazine

Promazine

Promazine
Systematic (IUPAC) name
N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine
Clinical data
AHFS/Drugs.com
MedlinePlus
Pharmacokinetic data
Protein binding 94%
Identifiers
CAS Registry Number  YesY
ATC code N05
PubChem CID:
IUPHAR/BPS
DrugBank  YesY
ChemSpider  YesY
UNII  YesY
ChEBI  YesY
ChEMBL  YesY
Chemical data
Formula C17H20N2S
Molecular mass 284.42 g/mol
 YesY   

Promazine (Sparine) is a medication that belongs to the phenothiazine class of antipsychotics. An older medication used to treat schizophrenia, it is still prescribed, alongside newer agents such as olanzapine and quetiapine. It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon either.

Promazine is not approved for human use in the United States. It is available in the US for veterinary use under the names Promazine and Tranquazine.