SCN10A

SCN10A

Sodium channel, voltage-gated, type X, alpha subunit
Available structures
PDB Ortholog search: RCSB
Identifiers
SCN10A Gene
Orthologs
SpeciesHumanMouse

Sodium channel, voltage gated, type X, alpha subunit also known as SCN10A or Nav1.8 is a protein which in humans is encoded by the SCN10A gene.[1]

Nav1.8 is a sodium channel subunit.[2][3][4]

Function

This subtype of voltage-gated sodium channel is expressed in nociceptors and has been proposed as a target for the development of new analgesics.[5]


In 2013, Bezzina & al showed that common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome.[6]

References

Further reading