SDB-005

SDB-005

SDB-005
Systematic (IUPAC) name
naphthalen-1-yl 1-pentyl-1H-indazole-3-carboxylate
Identifiers
ChemSpider
Chemical data
Formula C23H22N2O2
Molecular mass 358.17 g/mol

SDB-005 is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.[1] It is presumed to be an agonist of the CB1 and CB2 cannabinoid receptors. SDB-005 is the indazole core analogue of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group.

The code number SDB-005 was originally used for a different compound, the N-phenyl instead of N-benzyl analogue of SDB-006. This compound is a potent agonist of the CB1 receptor (Ki = 21 nM) and CB2 receptor (Ki = 140 nM).[2]

Original SDB-005

However SDB-005 was subsequently used as the name for the indazole-3-carboxylate compound mentioned above when it was sold in Europe as a designer drug, and was entered into the EMCDDA synthetic drug database under this name.[3] Consequently there are now two distinct, yet fairly closely related cannabinoid compounds, which may both be referred to under the code SDB-005.


See also

References

  1. ^ "SDB-005". Cayman Chemical. Retrieved 27 June 2015. 
  2. ^ "The Synthesis and Pharmacological Evaluation of Adamantane-Derived Indoles: Cannabimimetic Drugs of Abuse". ABS Chemical Neuroscience 4 (7): 1081–1092. July 2013.  
  3. ^ EWS_EU: Neue Psychoaktive Substanzen, April 2015