Sabcomeline

Sabcomeline

Sabcomeline
Systematic (IUPAC) name
(3R)-N-methoxyquinuclidine-3-carboximidoyl cyanide hydrochloride
Clinical data
Legal status
  • Never marketed
Identifiers
CAS number
ATC code None
PubChem
IUPHAR ligand
ChemSpider
UNII  YesY
ChEMBL
Chemical data
Formula C10H15N3O 
Mol. mass 193.12 g/mol

Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease.[1] It made it to phase III clinical trials before being discontinued due to poor results.

See also

References

  1. ^ Loudon JM, Bromidge SM, Brown F, et al. (December 1997). "SB 202026: a novel muscarinic partial agonist with functional selectivity for M1 receptors". The Journal of Pharmacology and Experimental Therapeutics 283 (3): 1059–68.